apalutamide will minimize the level or influence of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP3A4 inducer, with medication which can be CYP3A4 substrates may result in reduced exposure to these remedies.posaconazole will boost the stage o
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